Медичні та біологічні науки: міждисциплінарний аспект - 2025

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https://dspace.khimu-library.com.ua/handle/123456789/419

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Перегляд Медичні та біологічні науки: міждисциплінарний аспект - 2025 за Автор "Akbarov, E."

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  • Ескіз
    Документ
    Changes in liver tissue structure under the influence of moderate ischemia in conditions of enhanced antioxidant defense system
    (2025) Mirzayev, M.; Akbarov, E.; Farzaliyeva, S.
    This experimental study investigated the morphological changes in white rat liver tissue subjected to moderate ischemia (5 minutes) after prior administration of the antioxidant Mexidol. Histological examination 15 minutes post-ischemia showed no significant alterations in lobular architecture, hepatocyte integrity, or portal tract structures. Minor changes included slight edema, widened Disse spaces, and dilated, blood-congested sinusoids. Mild dystrophic changes were limited to some hepatocytes near the portal tracts. The results suggest a cytoprotective role of Mexidol and enhanced antioxidant defense in mitigating ischemia-induced liver injury, keeping changes within the limits of compensatory structural adaptation.
  • Ескіз
    Документ
    Mechanisms underlying the effects of hypobaric hypoxia on the thyroid gland
    (2025) Yagubova, S.; Sultanova, T.; Akbarov, E.
    The goal was to investigate the morphometric changes in the mesenteric lymph nodes (MLNs) of rats under conditions of experimental peritonitis. It is established that the MLNs respond rapidly to the spread of inflammation, showing signs of severe lymphadenitis. An analysis revealed significant hyperplasia of lymphoid follicles and a marked expansion of the medullary sinuses and subcapsular sinuses, indicating increased afferent lymphatic flow and active immunological response. It is substantiated that these changes reflect the barrier and drainage function of the lymphatic system during systemic inflammation. The conclusion is made that morphometric parameters of MLNs can serve as reliable indicators of the severity and stage of peritonitis, which is crucial for determining treatment strategies.