Наукові праці дослідників університету
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монографії, наукові статті, тези, доповіді
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Item type:Документ, Anatomical features of the ostiomeatal complex and their impact on complications in dental implantation(2025) Nazaryan, R.; Sosonna, L.; Iskorostenska, O.; Storozheva, M.; Fomenko, Yu.; Heranin, S.; Ohurtsov, O.; Nikonov, A.; Alekseeva, V.The anatomical structure of the ostiomeatal complex (OMC) plays a crucial role in the success of dental implantation procedures, particularly in the maxillary region. This study examines the anatomical variations of the OMC and their impact on postoperative complications in dental implantation. A total of 400 spiral computed tomography (CT) scans of patients aged 18 to 95 years were analyzed to assess key anatomical structures, including the maxillary sinus, concha bullosa, uncinate processes, and sinus ostium dimensions. Findings revealed significant anatomical variability, with concha bullosa observed in 33.2% of cases, uncinate process variations in 31.6%, and a narrowed maxillary sinus ostium in 6.25% of cases. These structural differences were found to influence sinus ventilation and drainage, thereby increasing the risk of postoperative complications such as sinusitis and impaired osseointegration. Statistical analysis highlighted strong correlations between sinus volume, bone thickness, and OMC components, reinforcing the need for thorough preoperative assessment. The study underscores the importance of personalized surgical planning and advanced imaging techniques in mitigating complications and optimizing dental implantation outcomesItem type:Документ, Morphometric thresholds of the ostiomeatal complex and their psychological correlates in sinus ventilation impairment(2025) Yurevych, N.; Kysylenko, K.; Sukhina, I.; Falova, O.; Khartsiy, O.; Rozhkova, O.; Lupyr, M.; Alekseeva, V.The ostiomeatal complex (OMC) is a critical anatomical region ensuring ventilation and drainage of the anterior paranasal sinuses. Variability in its morphology can lead to functional impairment and predispose individuals to chronic rhinosinusitis. Objective: To determine quantitative morphometric thresholds associated with inadequate sinus ventilation based on OMC structure and semilunar hiatus dimensions using CT data and computational modeling. Methods: Morphometric analysis was performed on 400 spiral CT scans. OMC parameters were measured manually and automatically, and 3D models were constructed. Pressure and flow simulations were conducted using the IMED system. Subjects were divided into three groups based on the width of the semilunar hiatus: narrow, moderate, and wide. Parameters such as sinus wall thickness, OMC component density, and estimated ventilation pressure were analyzed. Results: Both excessively narrow (<1.8 mm) and overly wide (>3.5 mm) semilunar hiatuses were associated with impaired ventilation. Optimal airflow occurred in the intermediate range (2.1–3.2 mm). A pressure gradient of <2.5 Pa between the maxillary sinus and nasal cavity was associated with stasis in 73% of cases. Strong correlations were observed between sinus ventilation efficiency and the thickness of the uncinate process (r = –0.75, p < 0.01), as well as medial maxillary sinus wall thickness (r = –0.72, p < 0.05). Conclusion: Functional ventilation of the maxillary sinus requires a semilunar hiatus width between 2.1 and 3.2 mm and a pressure differential above 2.5 Pa. Both morphological extremes are associated with physiological dysfunction, highlighting the importance of patient-specific anatomical assessment in surgical planningItem type:Документ, Anatomy of the maxillary sinus: implications for odontogenic sinusitis development(2024) Gorbik, E.; Ohurtsov, O.; Heranin, S.; Kolba, O.; Breslavets, N.; Sazonova, O.; Kysylenko, K.; Alekseeva, V.This study investigates the anatomical prerequisites that could contribute to the development of this condition. Material and methods: Using multi-slice computed tomography (MSCT), the study examined the structure and relationships of key anatomical features, including the alveolar process, sinus wall thickness, and the position of the teeth in relation to the maxillary sinus. The results revealed that the lower wall of the maxillary sinus is predominantly formed by the alveolar process, with significant variability in wall thickness, especially between the central and lateral regions. In 95% of cases, this wall was closely associated with the roots of the upper teeth, particularly the premolars. A strong negative correlation was observed between the thickness of the alveolar process and the volume of the maxillary sinus, suggesting that larger sinuses tend to have thinner alveolar processes. Additionally, a significant correlation was found between the position of the sinus and the degree of pneumatization, with a more medially positioned orbit in cases of reduced pneumatization.Conclusion: Structural features of the maxillary sinus, such as its proximity to the teeth and its relationship to sinus pneumatization, are critical factors in the development of odontogenic rhinosinusitis. A comprehensive, collaborative approach is necessary for effective management and prevention, with careful consideration of these anatomical aspects during dental and maxillofacial interventionsItem type:Документ, CT-based study of anatomical variations in chronic rhinosinusitis patients(2025) Yurevych, N.; Varzhapetian, S.; Buniatian, Kh.; Khotimska, Yu.; Sukhina, I.; Kuzmenko, N.; Trach, O.; Alekseeva, V.Introduction: Chronic rhinosinusitis (CRS) is frequently associated with anatomical variations that may predispose individuals to impaired sinus drainage and mucosal inflammation. Computed tomography (CT) of the paranasal sinuses provides an essential diagnostic tool for evaluating these variations. Objective: To assess the prevalence and types of anatomical variations in patients with CRS using CT Data. Material and Methods: A retrospective cross-sectional study was conducted on 75 patients diagnosed with CRS. CT scans were evaluated for anatomical variations including concha bullosa, deviated nasal septum, agger nasi cells, Haller cells, Onodi cells, uncinate process variations, and paradoxical middle turbinate. Results: The most frequent variation observed was concha bullosa (64%), followed by deviated nasal septum (61.3%), agger nasi cells (49.3%), and Haller cells (32%). Onodi cells were observed in 21.3% of patients, uncinate process variations in 17.3%, and paradoxical middle turbinate in 12%. Conclusion: Anatomical variations are common in CRS patients and can play a critical role in the pathophysiology of the disease. CT imaging is vital in identifying these variations, which can guide appropriate surgical planning.Item type:Документ, Аnatomical variability of the ethmoid and sphenoid sinuses(2025) Yurevych, N.; Pokotylo, Р.; Podoliuk, M.; Seleznova, R.; Voinytska, O.; Vdovichenko, V.; Sukhonosov, R.; Alekseeva, V.The ethmoid and sphenoid sinuses exhibit marked anatomical variability that can impact surgical approaches and predispose individuals to complications during sinus and skull base procedures. Objective: To characterize the morphometric patterns and anatomical variants of the ethmoid and sphenoid sinuses based on high-resolution CT data and to analyze their surgical and clinical significance. Methods: A total of 400 CT scans were analyzed. Sinuses were classified by pneumatization type, dimensions, and presence of anatomical variants. 3D reconstructions were performed to assess spatial orientation and proximity to neurovascular structures. Results: Ethmoid sinus complexity was classified into three distinct types, with higher complexity correlating with narrower surgical corridors and increased risk of incomplete ethmoidectomy. Sphenoid pneumatization showed significant variability, including presellar, sellar, and postsellar types. Onodi cells were identified in 13% of cases, closely related to the optic canal. Septated sphenoids were present in 21%, often traversing the internal carotid artery canal. Conclusion: Detailed anatomical understanding of posterior sinus morphology and variation is essential for safe and effective sinus and skull base surgery. This study provides a morphometric atlas to support individualized surgical planningItem type:Документ, Anatomical variability of the alveolar process of the maxilla based on multislice computed tomography data(2024) Shiyan, D.; Kysylenko, K.; Trach, O.; Yurevych, N.; Lupyr, M.; Alekseeva, V.Modern research methods, widely implemented in routine medical practice, open new horizons for the study of anatomical structures. The maxilla is one of the regions of the human skull that shows significant variability with age and gender. This is due to the peculiarities of tooth eruption and age-related changes in the periodontium and adjacent structures, which undoubtedly affect the structure of the alveolar process, sometimes drastically altering it over time.Item type:Документ, Anatomical Features of the Carotid Arteries, Ophthalmic Nerves, Mandibular Nerve and Extraocular Artery Based on Multislice Computed Tomography (MSCT) Data(Georgian Association of Business Press, 2026) Kalashnik-Vakulenko, Yu.; Kostrovskyi, O.; Aleksandruk, N.; Makaruk, O.; Kudriavtseva, T. O.; Lytovska, O.; Leliuk, O.; Alekseeva, V.Introduction: Anatomical variability of cranial neurovascular structures presents significant challenges in surgical planning and diagnostic interpretation. Multislice Computed Tomography (MSCT) offers detailed imaging of these structures, facilitating accurate morphometric analysis and spatial understanding critical to clinical interventions. Objective: To analyze the anatomical features and variations of the internal carotid arteries, optic and ophthalmic nerves, mandibular nerve, and extraocular (ophthalmic) artery based on high-resolution MSCT imaging data. Materials and Methods: This retrospective study evaluated 400 MSCT scans performed using a Toshiba Aquilion 64-slice scanner. Image analysis included multiplanar reconstructions and 3D modeling using RadiAnt DICOM Viewer. Measurements focused on ICA diameter and proximity to the sphenoid sinus, optic canal integrity, mandibular canal course and size, and traceability of the ophthalmic artery. Statistical analysis was performed using SPSS v26 with significance set at p<0.05. Results: 1. ICA was adjacent to the sphenoid sinus in 97% of cases; dehiscence occurred in 11%. 2. Optic canal dehiscence was found in 13.5%, with average diameter of 3.7±0.5 mm. 3. Mandibular canal showed 9% asymmetry; mean diameter was 2.9±0.4 mm. 4. Ophthalmic artery was visualized in 78% of scans; mean diameter 1.5±0.2 mm. Significant interindividual variability was noted across all structures. Conclusion: MSCT is an effective tool for evaluating cranial neurovascular anatomy. Frequent anatomical variations such as ICA dehiscence and mandibular canal asymmetry underscore the need for individualized imaging assessment in preoperative planning. The high resolution of MSCT allows reliable visualization of fine neurovascular details, enhancing safety in head and neck surgery.