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Mechanisms underlying the effects of hypobaric hypoxia on the thyroid gland
(2025) Yagubova, S.; Sultanova, T.; Akbarov, E.
The goal was to investigate the morphometric changes in the mesenteric lymph nodes (MLNs) of rats under conditions of experimental peritonitis. It is established that the MLNs respond rapidly to the spread of inflammation, showing signs of severe lymphadenitis. An analysis revealed significant hyperplasia of lymphoid follicles and a marked expansion of the medullary sinuses and subcapsular sinuses, indicating increased afferent lymphatic flow and active immunological response. It is substantiated that these changes reflect the barrier and drainage function of the lymphatic system during systemic inflammation. The conclusion is made that morphometric parameters of MLNs can serve as reliable indicators of the severity and stage of peritonitis, which is crucial for determining treatment strategies.